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The Ferret Veterinary Handbook
1.  Classification
	A.  Carnivore-Mustelid-related to weasel's, skunks, otters, minks, etc.  

	B.  Species-Mustela putorious furo-domestic Ferret-comes in a variety of 
 	    colors and color patterns.  Most common colors are Sable (was dark  
	    brown with cream to white under code), chocolate (his a lighter, 
	    warmer version of the Sable), Albino, and silver. 
2.  History
	A.  Documented introduction into the U.S. in the late 1800s for the for 
	    industry and for rodent control one farms. Possible early arrival of 
	    individual levels kept as family pets or private stock.  Current 
	    estimate of ferrets in the U.S. is between 6 and 8 million.  

	B.  Originally used in Europe and Asia for hunting wraps and rabbits.  

	C.  Ferrets are domesticated animals and have been raised in captivity 
	    for thousands of years.  Records show that ancient Egyptians used 
 	    them performing vermin control.  

	D.  Ferrets are legal in some states and cities.  A few states require  
	    permit to own ferret. 
3.  Characteristics
	A.  Lifespan - is five - eight years average.  ('s 14 and 1/2 years is  
	    record). Geriatric problems start about three years of age.  

	B.  Weight - males one - 2.5 kg; females 0.5 - 1 kg.  There's a normal  
	    playing - 40 percent weight fluctuation due to subcutaneous fat  
	    accumulation in the fall and laws of same in the spring.  This is 
 	    generally more noticeable in intact animals.  Ferrets usually reach 
	    adult weight between six to eight months.  

	C.  Hair molt is heaviest in spring and less so in the fall.  Color length 
	    and texture of code may change significantly with each mold.  (Example: 
	    pure colored ferrets may become black dyed whites by four to five  
	    years of age.  The mask on Sable's and chocolates may be lost each 
	    winner in return in the fall.)  

	D.  Males have a J. shaped penis which is difficult to catheterize.  

	E.  Heat loss by panting, few and poorly developed sweat glands, very heat 
	    intolerant (heat stress may start at 80 degrees).  

	F.  Dental formula 3-1-3-1 deciduous teeth here errupt at 14 days and  
			   3-1-3-2 
	    permanent canines at 47-52 days of age.  

	G.  No cecum present, differentiation of small and large intestines.  

	H.  14 thoracic vertebrae, and 6 lumbar vertebrae, 14 pairs of ribs.  

	I.  Paired anal glands.  These are not necessary to remove as a routine  
	    procedure. We recommend to surgery only for those ferrets with chronic 
 	    anal gland impactions, anal gland disease, and for those few ferrets 
 	    that express the anal glands frequently. Neutering will alleviate 
	    the strong body odor which originates in the skin oils in intact 
 	    animals. 
4.  Diet
	A.  Carnivorous, ferrets don't digest fiber well, so keep fruit and  
	    vegetable matter to a minimum.  

	B.  Very high protein requirement, 30 percent minimum.  Due to short GI 
	    transit time, amino acids have to be very high quality and highly 
	    adjustable.  

	C.  High-quality kitten/Ferret food is recommended.  (A high-quality cat 
	    food should be used for ferrets over three years of age).  Cooked  
	    meat can also be added.  

	D.  Fatty acid supplements, should be used in moderation.  Are it  
	    especially helpful for ferrets with dry coats or in cold or dry 
	    climates.  

	E.  Hair ball laxative (feline type), is extremely helpful in the  
	    prevention of hair balls, which are very common in the Ferret.  
 	    Use 1/4 teaspoon every other day.  During daily shedding seasons.  

	F.  Food should be available to all times.  Ferrets need to snack  
	    throughout the day.  

	G.  Appetite may drop off during the spring breeding season in intact 
	    animals (especially males.)  

	H.  Anorexia or finicky animals, can be given strained meat human baby 
 	    food by syringe. NutriCal or similar products are also well liked.  
	    Feline nutritional supplements may also be used. 
5.  Reproduction
	A.  Males are Hobs, females are Jills and the young are Kitts or sometimes 
 	    pups (European).  Neutered males are sometimes referred to as Gibbs 
	    and spayed females as Sprites.  

	B.  Puberty is reached by four to nine months, usually the spring after 
	    birth.  

	C.  Fertility lasts three to four years. 

	D.  Females are seasonally polyestrus from March to August.  This  
	    stimulated by the increase of the photo-period.  The vulva enlarges 
	    significantly, there is a clear view choroid discharge, but no blood. 

	E.  Reflux ovulator, regresses one to three weeks after breeding.  They  
	    can remain in estrus for months, which may lead to a fatal  
	    non-regenerate to anemia (caused by high per estrogenism).  Estrus  
	    can be terminated with 100 units of HCG given intramuscularly or  
	    subcutaneously after the animal has been in estrus for the least ten 
	    days.  Repeat either product after two weeks if vulvar swelling is 
 	    not reduced.  Will come back into heat in one to four modes.  Due to 
 	    a CB see if the animal has been in estrus for four weeks or longer.  
	    Vasectomized males have also been used to successfully take females 
 	    out of estrus, but this method is not 100 percent reliable. 

	F.  Due to use progesterone products to take ferrets out of estrus, it 
	    can lead to pyometra. 

	G.  Males are also seasonally federal, dependant on the photo-period.   
	    Testicles to be appreciably smaller in the winter. 
6.  Clinical pathology values
	A.  Urine pH 6.527 to 5 with mild to moderate proteinuria discounting 
	    and normal year and may also give a false Ketone value. 

	B.  Feces are soft tubular and formed. 

	C.  His probation and 33 to 35 times per minute. 

	D.  Rectal temperature 100 to 103 degrees (101.9 average). 

	E.  Blood volume 60 to 80 ml per kg 

	F.  Heart rate 216 to 250 (225 average). 

	G.  PCV 42 to 61 percent (49 average). 

	H.  RBC 6.8 to 12.2 X 10 6/mm3. 

	I.  Hemoglobin 16.50 G./DL. 

	J.  WBC 5.9 X 103/mm3. 

	K.  Platelets (10 3/mm3) - 297 - 910. 

	L.  Total protein (G./DL) - 5.1 - 7.4 (6.0 average). 

	M.  Albumen - 3.5 G./DL. 

	N.  Glucose (fasting) 94 to 125 
	           (non- fasting up to 207). 

	O.  BUN - 10 - 45 mg/DL (21 average). 

	P.  Alkaline Phosphotase 9 to 84 IU/L 
	           (38 average). 

	Q.  SGOT; SAST 28 to 120 IU/L (95 average). 

	R.  Total Bilirubin  1.0 mg/DL. 

	S.  Creatinine 0.4 to 0.9 mg/DL. 

	T.  See him 137 to 162 mmol/L (148 average). 

	U.  Potassium 4.5 to 7.7 (5.5 average). 

	V.  Chloride 106 to 125 mmol/L (116 average). 

	W.  Calcium 8.0 to 11.8 mg/L (9.5 average). 

	X.  Phosphorus 4.0 to 9.1 mg/DL (5.9 average). 

	Y.  Insulin 0 to 20 (if fasting to glucose is below 65 even in cases of 
	    insulioma the insulin level may appear normal). 
7.  Restraint and anesthesia 
	A.  Manual Restraint 
		1.  Gentle restraint is generally all that is necessary.  Do not 
 		    use gloves. 

		2.  Try scruffing the pet for cleaning, injections, nail trims and 
		    abdominal palpitations.  Grasp the skin right behind the ears  
		    and over the back of the neck and suspends the Ferret over a 
 		    table. 
	B.  Chemical Restraint. 
		1.  Isofurane is highly recommended.  The Ferret can be masked  
		    down and maintained on a mask or intubated. 

		2.  Ketamine HCL plus acepromazine in a 10 to 1 ratio can be used 
		    at 35 to 40 mg per kilo kg of ketamine for surgical anesthesia 
		    and at 10 mg per kg for light sedation. 

		3.  Ketamine HCL and diazepam may also be used its 25 mg per kg of 
		    ketamine and 2 mg per kg of diazepam. 

		4.  Xylazine should be used with caution, deaths in healthy  
		    animals have been reported. 
8.  Blood collection and injection techniques 
	A.  Tail artery is is easiest without sedation.  You can use a treat as a 
	    distraction. Use a 25 gauge needle and TB syringe and insert the  
	    needle at about a 45 degree angle into the ventral tail about 1 to 2 
	    in. from the tail base.  Move needle up-and-down gentle suction until 
	    you hit the artery and thought up sample. 

	B.  The jugular vein, cephalic and recurrent tarsal can also be used with 
	    or without sedation, non-anesthetized animal can be restrained for a  
	    cephalic or jugular veinipuncture a similar manner as a cat.  Use a  
	    25 gauge needle for all.  (Can use 22 gauge for jugular) 

	C.  Toe nail should not be used except in cases were blood can not be  
	    obtained elsewhere; this is very painful and doesn't yield much. 
	D.  Anterior vena cava may also be used, the animal must be very well 
	    restrained. 

	E.  Cardiac puncture can be used when a large central blood is required as 
	    in the case of a donor animal for blood transfusion.  20 cc of lead  
	    may be removed in this matter from a male Ferret weighing 1 kg without 
	    ill effects.  12 cc may be removed from a female weighing.75 kg. 

	F.  Injections can be given subacutaneous over the neck area while  
	    scruffing the animal, or intramuscularly in the thigh or lumbar area. 

	G.  IV catheters can be placed in the cephalic or jugular veins.  Knicking 
	    the skin with a blade may be necessary to get the catheter through 
	    without damaging it. 
9.  Vaccinations 
	A.  Canine Distemper 
		1.  It is absolutely necessary to vaccinate for this disease.  It 
		    is essentially 100 percent fatal in the Ferret. 

		2.  Use highly attenuated MLV chick embryo vaccine.Fromm-D by  
		    Solvay has proven to be quite safe and effective. Fervac D by 
		    united vaccines is also available and is the only the stem 
		    per vaccine currently approved by the USDA for use in  
		    ferrets. 

		3.  It is not necessary to use vaccines with parvo virus,  
		    leptosoirosis, parainfluenza, hepatitis, corona virus. 

		4.  First vaccination in kits is at six weeks, then repeated at 
		    eight weeks, 11 weeks, and 14 weeks. 

		5.  Immunity may last up to three years, but we recommend to  
		    re-vaccinate annually, because breaks in vaccine have been  
		    seen at 18 months. 

		6.  Pregnant females may be vaccinated. 

		B.  Feline panleukopenia -- it is not necessary to vaccinate for 
 		    this disease.

	C.  Rabies 
		1.  Currently available vaccine is Pittman Moore's Imrab 3. 

		2.  First dose given three months and then annually. 

		3.  Never use live  vaccine as it may induce clinical rabies.
 
		4.  Check local regulations, as some state or localities may not 
		    recognize or approve of the vaccine. 

	D.  Botulism C Toxoid - only for commercially raised animals, especially if 
	    being fed raw meat.  Vaccinate at weaning, then annually. 

	E.  Feline leukemia - no current data indicates that this vaccine should  
	    be used in ferrets.
 10.  Surgical proceedures 
	A.  Castration can be performed either by a prescrotal incision as in the 
	    canine or through two scrotal incisions as in cat.  It is done at 
	    four to six months of age and greatly decreases the ferrets body  
	    odor. 

	B.  Monorchids are usually subcutaneous but may also be abdominal. 

	C.  OHE is performed in the same manner as in the feline and is done at 
	    four to six months of age.  It can be done during estrus with no ill  
	    effects to the Ferret or stress to the surgeon unless the animal has 
 	    been in estrus one-month or longer.  (See E. below) 

	D.  Non-breeding females should be spayed to prevent the development of 
	    fatal non-regenerative anemia that may occurred during persistent 
	    estrus. If a female has been in estrus for 4 weeks or longer perform 
	    a see CBC and platelet count prior to surgery. 

 

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